Nestled along historic Highway 19, Little White Guest House offers an intimate retreat where refined comfort meets the quiet charm of the Missouri countryside.
"Where every detail is considered, every moment is unhurried, and every guest is received as family."
A serene retreat featuring a plush king bed, hand-selected linens, and views of the garden courtyard.
Spacious and light-filled with a private garden patio, sitting area, and artisan-crafted furnishings.
Honoring the character of New Florence with period-inspired décor, a queen bed, and curated reading nook.
Little White Guest House was born from a simple conviction: that travelers deserve more than a place to sleep—they deserve a place that feels like home, refined.
Each morning begins with a freshly prepared breakfast using ingredients from local farms. Afternoons unfold at a leisurely pace among our gardens, and evenings invite you to linger in a room where every detail has been thoughtfully considered.
Personalized recommendations for wineries, hiking trails, and the hidden histories of New Florence.
A generous breakfast featuring seasonal produce from Missouri farms, served in our sunlit dining room.
With only a handful of rooms, we ensure every guest receives personalized attention and undisturbed privacy.
Some places you visit. Others you carry with you. We hope Little White becomes the latter.
Situated on the historic Route 66 corridor, our guest house offers easy access to the rolling hills of the Missouri countryside while remaining a peaceful retreat from the road.
We'd love to welcome you to Little White Guest House. Reach out by phone or complete the form below, and we'll respond within 24 hours to confirm your reservation.
261 S Highway 19
New Florence, MO 63363
Check-in: 3:00 PM — 8:00 PM
Check-out: 11:00 AM
Late arrivals: Please call ahead to arrange
Your reservation request has been received. We'll be in touch within 24 hours.